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Many patients experience side effects when starting treatment, and most improve within the first 12 weeks
A concrete example that clarifies this boundary is gastrin: multiple adequately powered human trials demonstrated that gastrin-based therapies failed to preserve beta-cell function in type 2 diabetes, and development was largely discontinued by approximately 2010
Muscle strength relative to body weight increased across all active treatment groups compared with placebo, because of decreased body weight and preserved absolute strength
Canada offers several effective alternativesboth medications and lifestyle-based strategiesthat can support weight management and type 2 diabetes care
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